The Impact of Maternal Obesity on the Development and Outcomes of Congenital Masses: A Review

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dc.contributor.authorSarita Jangra
dc.contributor.authorAmit Sharma
dc.contributor.authorThakur Gurjeet Singh
dc.contributor.authorBhavesh Dharmani
dc.contributor.authorTanya Sood
dc.contributor.authorKritika Sharma
dc.contributor.authorBhupinder Bhyan
dc.contributor.authorYousef Saeed Alqarni
dc.contributor.authorFahad Thabet Alsulami
dc.date.accessioned2025-12-19T09:29:17Z
dc.date.available2025-12-19T09:29:17Z
dc.date.issued2024-04-20
dc.description.abstractBackground: The global prevalence of obesity has risen sharply, including among pregnant women, contributing to a significant increase in obstetric complications and adverse birth outcomes. One such concern is the development of congenital anomalies, which include cystic, solid, or vascular malformations. These anomalies are influenced by maternal factors such as pre-pregnancy malnutrition, inadequate folic acid intake, iodine deficiency, consanguineous marriages, insufficient immunization, and exposure to teratogens like alcohol. Addressing the high morbidity associated with these abnormalities requires a deep understanding of their anatomical and etiological factors. Purpose: This review aims to examine the impact of maternal obesity on the development and outcomes of congenital masses. It seeks to identify mechanisms underlying these malformations, assess their prevalence, and explore strategies for prevention and management. Method: A comprehensive literature review was conducted, focusing on studies that link maternal obesity with congenital anomalies. Relevant articles were identified from databases such as PubMed, Scopus, and Web of Science using keywords like “maternal obesity,” “congenital masses,” “foetal malformations,” and “pregnancy outcomes.” Results: Maternal obesity was associated with an increased risk of congenital anomalies due to factors such as altered metabolic states, inflammation, and suboptimal nutrient levels. Early diagnosis and intervention were identified as critical for improving outcomes. Conclusion: Maternal obesity significantly impacts the development and outcomes of congenital masses. Effective prevention strategies, such as nutritional counselling, obesity management, and early screening programs, are essential to mitigate these risks and improve maternal and neonatal health outcomes.
dc.identifier.issn2321-2217
dc.identifier.issn2321-2225
dc.identifier.otherhttps://doi.org/10.15415/jptrm.2024.121005
dc.identifier.urihttps://demodspace.chitkara.edu.in/handle/123456789/294
dc.language.isoen
dc.publisherChitkara University Publications
dc.subjectObesity
dc.subjectMalformation
dc.subjectPregnancy obesity
dc.subjectCongenital defects
dc.subjectPaediatric neoplasm
dc.subjectMaternal obesity
dc.subjectCongenital anomalies
dc.subjectPaediatric neoplasms
dc.subjectStill birth
dc.titleThe Impact of Maternal Obesity on the Development and Outcomes of Congenital Masses: A Review
dc.typeArticle

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JPTRM Vol. 12 No. 1 (May 2024)