Synthesis,Characterization and Biological studies on Mannich Bases of 2-Substituted Benzimidazole Derivatives

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dc.contributor.authorRitchu Sethi
dc.contributor.authorSandeep Arora
dc.contributor.authorSandeep Jain
dc.contributor.authorNeelam Jain
dc.date.accessioned2025-12-16T07:01:19Z
dc.date.available2025-12-16T07:01:19Z
dc.date.issued2015-05-20
dc.description.abstractIn the present study novel derivatives of 2-substituted benzimidazoles were prepared via Mannich reaction and evaluated for their in vitro antimicrobial activity against two gram negative strains (Escherichia coli and Pseudomonas aeruginosa), two gram positive strains (Bacillus subtilis and Staphylococcus aureus) and fungal strains (Candida albicans and Aspergillus niger).The synthesized compounds were also screened for antioxidant activity.The newly synthesized compounds were characterized by spectral and analytical techniques.The results revealed that all the synthesized compounds have a significant antioxidant and biological activity against the tested microorganisms.
dc.identifier.issn2321-2217
dc.identifier.issn2321-2225
dc.identifier.otherhttps://doi.org/10.15415/jptrm.2015.31005
dc.identifier.urihttps://demodspace.chitkara.edu.in/handle/123456789/182
dc.language.isoen
dc.publisherChitkara University Publications
dc.subjectMannich Bases
dc.subjectantimicrobial activity
dc.subjectantioxidant activity
dc.titleSynthesis,Characterization and Biological studies on Mannich Bases of 2-Substituted Benzimidazole Derivatives
dc.typeArticle

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JPTRM Vol. 3 No. 1 (May 2015)