Journal of Pharmaceutical Technology, Research and Management

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https://demodspace.chitkara.edu.in/handle/123456789/15
The Journal of Pharmaceutical Technology, Research and Management (JPTRM) is a multidisciplinary, open access journal published as part of the Chitkara University Publications journal series. The journal is dedicated to fostering innovation, collaboration, and knowledge exchange within the global pharmaceutical sciences community. JPTRM aims to provide a streamlined submission and peer review process, ensuring timely publication and a high level of author support at every stage. The journal welcomes high-quality, original research, reviews, and case studies from all areas relevant to pharmaceutical science, technology, and management. Key areas of focus include, but are not limited to: Pharmaceutical formulation and drug delivery systems Biotechnology and nanotechnology applications in pharmacy Quality control, validation, and regulatory sciences Pharmaceutical manufacturing and industrial processes Supply chain management and pharmaceutical operations Pharmacoeconomics and strategic management in healthcare Digital health, automation, and AI in pharmaceutical development Policy, ethics, and global trends impacting the pharmaceutical industry The journal serves as a platform for researchers, industry professionals, and policy-makers to contribute to the advancement of pharmaceutical knowledge in sustainable practices. Submissions that demonstrate interdisciplinary approaches or have practical implications for pharmaceutical innovation and management are especially encouraged. All papers are evaluated on the basis of scientific content. Submissions are first screened for research and publication ethics prior to peer review. The journal reviews each submission from a sound science perspective.

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Browsing Journal of Pharmaceutical Technology, Research and Management by Subject "14α-demethylase"

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    Molecular Docking Approach to Identify Potential AntiCandidal Potential of Curcumin.
    (Chitkara University Publications, 2020-11-17) Nidhi Rani; Prerna Sharma; Praveen Kuma
    Background: Candida albicans is a kind of fungus that can lead to mortality. In the presence of the enzyme Lanosterol-demethylase, Ergosterol, the major sterol in the fungal cell membrane, is the resulting product of Lanosterol (Cytochrome P450DM). Purpose: Azole antifungal drugs target this enzyme as a target enzyme. The work included selecting and modelling the target enzyme. Cucumin’s inhibitory effect on Cytochrome P450 was tested utilising molecular docking experiments. Methods: Chem sketch was used to create compound structures, and Molergo Virtual Docker was used to do molecular docking. Results: All of the curcumin and conventional medicines, such as Ketoconazole, Clotrimazole, and Miconazole, have interaction with 14-demethylase amino acid residues, Haem and water molecules in the target site, as per the docking research.