Browsing by Author "Poonam Arora"

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    Ameliorative Potential of Aminophylline In Restrain Stress Induced Behavioural and Biochemical Alterations
    (Chitkara University Publications, 2017-11-02) Rajneet Kaur; Manjinder Kaur; Poonam Arora
    This study is designed to investigate the attenuating prospective of aminophylline in immobilization stress generated behavioural changes in rats. Animals were exposed to restrain stress before being subjected to varying doses of aminophylline (1mg/kg, 2mg/kg and 4mg/kg). Behavioural changes were analyzed to assess the intensity and the degree of the stress, by estimating the changes in the exploratory behaviour, spontaneous activity and social behaviour using various paradigms. As a consequence of stress, the behavioral patterns so changed were assessed in the terms of changes in the locomotor activity, number of head dips and increased avoidance behaviour. Aminophylline (4mg/kg) modulated the stress produced changes in the behaviour and oxidative stress generated biochemical alterations in a significant manner (p<0.001). The results so obtained suggest that upon exposure to stress, animal behavioural patterns, biochemical markers levels changed and these changes wereefficiently modulated by aminophylline at therapeutic doses.
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    Improving Physicochemical Properties of Repaglinide Through Pharmaceutical Adduct Formation
    (Chitkara University Publications, 2020-05-20) Sharen Gill; Poonam Arora
    Background: Many formulation strategies are presently in development in pharmaceutical industry. However, the formation of pharmaceutical adducts is considered to be the most appropriate technique for improving the drug solubility and dissolution as no chemical bond changes are involved in this technique. Purpose: This technique is highly used for compounds which are not able to give viable formulation products with standard techniques such as salt formation and polymorph generation. In the present study, this method is applied to repaglinide, which is an hypoglycemic agent, with compromised solubility. Methods: The adducts were prepared by slow evaporation method and characterized using DSC, FTIR and PXRD studies. The solubility and dissolution studies were carried out to determine the increased solubility of drug in adducts. The drug amount interacted with coformers has also been determined. Results: The present study demonstrates the improvement in solubility and thus dissolution of repaglinide in adducts. Conclusion: The adducts formed in the present study can be further exploited to prepare formulation of repaglinide adducts with better physicochemical characteristics.
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    Performance Appraisal in the Era of New Normal
    (Chitkara University Publications, 2020-04) Nitika Kaushik; Poonam Arora
    Performance Appraisal is the process of assessing the accomplishments of workforce & to ac­knowledge their capabilities for facilitating development. Performance evaluation is one of the areas in Human resource management which is considerably affected by the spread of pandemic severe acute respiratory syndrome corona virus 2. This virus outbreak posed new challenges for the companies across the globe. As a result in order to tackle this uncertainty various organiza­tions have taken measures to cut down the expenses like deferment in the appraisal cycle or for muted salary increments. Thus one of the objectives of this paper is to study the impact of Covid -19 on performance appraisal of employees. Further this pandemic is equally challenging for the managers also. As social distancing and working remotely have become a new normal, employees work remotely from each other and from managers, and this will be more common in the fu­ture. Managers are now searching for new ways to ‘do visibility’ without always being physically present. It has also become the vital demand of the situation as managers must be aware of the circumstances in which employees are working in. Therefore another objective of this paper is to suggest an approach to manage the performance evaluations of remote working employees. It is recommended that managers should adopt the choice based approach for performance evaluation instead of control based approach. The review is formed on articles and reports from various internet sources and journals. Further some ways of managing the performance assessment of remotely working employees and scope for the future are also discussed.
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    Redesigning Human Resource Management System through Cloud Computing: A Strategic Approach
    (Chitkara University Publications, 2019-10) Poonam Arora
    Cloud computing is enabling human resource (HR) management functions to strategically integrate into business operations. Its acting as a game changer for HR amid intense competition to survive and grow. Digital disruption, transformation, agility has set the new benchmarks for organizations to automate and redesign their functions. Cloud Computing offers HR a completely new dimension with cloud centric benefits like reduction in communication gap, increased organizational excellence, effective talent strategies, data driven decision making, and supporting revenue in organizations. Cloud Computing has the right capability to redesign major HR functions with agility to match the changing requirements of business, automating transactional activities, smarter decision making and meeting the business expectations. Use of HR cloud in organization can result into structural benefits beyond technological advancements. Cloud HR gives organizations flexibility of location, prompt information processing, effective use of data analytics and strategic decision making. This paper discusses ways through which cloud computing could be integrated into HR functions. An analysis on applications of cloud computing in human resource areas with their outcomes is also presented in this paper. A brief note on future prospects of cloud computing in HRM is also discussed.