Browsing by Author "Neha Sharma"

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    Predicting The Potential of Convolvulus Pluricaulis Against Cognitive Dysfunction With The Help of Prediction of Activities Spectra of Substances Software
    (Chitkara University Publications, 2022-11-10) Vikas Sharma; Navneet Khurana; Sakshi Sharma; Soumik Chaudhury; Samriti, Talluri Sriram; Neha Sharma
    Objective: Cognitive dysfunction appertains to a loss in verbal, non-verbal learning, attention, working and short-term memory, motor functioning, problem-solving, and processing speed. The major objective of this study is to find out phytoconstituents obtained from Convolvulus Pluricaulis with the help of PASS software, which can be used in the treatment of cognitive dysfunction. Methods: PASS is important software used in this study to find out biological activity spectra of phytoconstituents of Convolvulus Pluricaulis in the amelioration of cognitive dysfunction. The predicted biological activity was also compared with marketed compounds like Rivastigmine, donepezil, memantine, and curcumin. Results: From the study, it was found that CP has great potential in the treatment of cognitive dysfunction. Many phytoconstituents of CP have free radical scavenging, antioxidant, and dementia treatment activity. Conclusion: In this research work, information was compiled with the help of PASS software of phytoconstituents of Convolvulus Pluricaulis for its potential against cognitive dysfunction. Further research is required to explore the potential of CP phytoconstituents in the treatment of cognitive dysfunction.
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    Prediction of the Anti-Parkinson’s Effect of Phytoconstituents from Mucuna Pruriens with the use of Prediction of Activities Spectra of Substances Software
    (Chitkara University Publications, 2022-11-10) Sakshi Sharma; Navneet Khurana; Vikas Sharma; Soumik Chaudhury; Samriti, Talluri Sriram; Neha Sharma
    Mucuna pruriens Linn is the most popular plant which has been used for a long time for treating many diseases. The plants shows wide pharmacological activities like antidiabetic, antineoplastic, antiepileptic, aphrodisiac, antimicrobial activities etc. It has wide use in the treatment of the Parkinson’s disease. The rationale behind this study is to discover the maximum activities over the selected phytoconstituent of the plant Mucuna pruriens which can be used in Parkinson’s disease. With the help of Prediction of activities spectra of substances (PASS) software activities which are useful in the management of Parkinson’s disease can be recognized. The mol file of the compounds was downloaded from Pubchem and the activity of the various compounds was speculated in the PASS software. From the data we have noted the Pa values of the compounds and the related activities of the compounds then we have predicted the reported activities of the compounds and from the table and graph we have observed the higher and lowest value of the compounds showing different activities and also observed which are the compounds which does not show the activities.
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    Rising Toll of Frauds in Banking: A Threat for the Indian Economy
    (Chitkara University Publications, 2018-04) Neha Sharma; Dhiraj Sharma
    Banking is a process which predicts the relationship between sources of funds and their application. The basic process of banking helps the society to bridge the gap between availability and usage of these available funds in a correct manner. Over the years the banks have developed in a very big way, and with the growth of banking business, banking frauds have taken birth. The history of banking frauds is almost as old as the banking startup. Today, bank frauds have taken all possible forms and are prevalent in every facet of banking. There is a spirited need for banks to always stay alive to threat of frauds, build strong systems that can shield, pre-empt frauds, continuously monitor and review the efficiency of such preventive systems. To succeed in controlling frauds, banks need to be proactive and pre-emptive. This study establishes a theoretical framework with regards to banking frauds in the Indian context as well as shows the picture of frauds in banking sector outside India. By reviewing various studies in the area of banking frauds the paper built a research model which further helps to find out various types of frauds and reasons for the same, and will definitely give new scope to further studies. The present study sheds light on the area by reviewing various studies in the field of banking frauds. The study helps to find out the growth and trends of frauds in the banking sector and specially focuses on Indian Banking sector, as at present there are very few studies which give an in-depth insight of frauds in banking sector. Further the study also reviews the role of employee and customer with regard to banking fraud studied which is primarily needed in the context of Indian Banking system. The present study is conducted by collecting secondary data from the published and unpublished Sources, Government Publications, journals, magazines, books and periodicals etc
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    Understanding the Role of Muscle Coordination Impairments in Central Nervous System Disorders
    (Chitkara University Publications, 2024-04-20) Josephat Gaudence Kipesha; Harshpreet kaur; Navneet Khurana; Neha Sharma
    Background: The central nervous system (CNS) regulates the precise activation of motor units, which is vital for muscle coordination and goal-directed movement. The CNS modulates motor unit firing rates to control force production during muscle contraction. Many CNS diseases, such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, and anxiety-related disorders, are linked to abnormalities in muscle coordination. Purpose: This review examines the complex connection between CNS disorders and impairments in muscle coordination, highlighting the roles of motor performance, neurodegeneration, and cerebellar function. Methods: A comprehensive review of recent literature was conducted to analyze the neurophysiological mechanisms underlying motor dysfunction. Studies involving kinematic analyses describing movement abnormalities in anxiety and depression were reviewed. Results: Neurodegenerative processes contribute to muscular dysfunction, often occurring without anatomical alterations in muscle tissue. Declining motor performance and neurodegenerative changes suggest that early motor impairments may serve as potential indicators of CNS pathology. Conclusion: Understanding the link between CNS disorders and muscle coordination impairments is crucial for distinguishing drug-induced muscular effects from symptoms of neurological diseases, guiding the development of more targeted treatments.