Browsing by Author "Neelam"

Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    Formulation, Optimization and Evaluation of Sustained Release Microspheres using Taguchi Design
    (Chitkara University Publications, 2014-05) Sukhbir Singh; Sandeep Arora; Neelam; Dharna Allawadi
    The aim of present study is to prepare microspheres of eudragit RL 100 loaded with Nefopam Hydrochloride by single emulsion solvent evaporation technique. Taguchi L9 orthogonal array design has been used to optimize the composition and operating conditions for preparation of formulations. Nine batches (F1-F9) were prepared by taking three independent variables (X1- drug: polymer ratio, X2- stirring speed and X3- stirring time) at three levels (+1, 0, -1). Response variables studied for batches (F1-F9) were mean particle size (μm) (Y1), drug entrapment efficiency (% w/w) (Y2) and drug loading (% w/w) (Y3). Drug- polymer compatibility study was carried out by DSC and FTIR spectroscopy and indicates no physicochemical interaction. Microspheres were analyzed for morphological characteristics, mean particle size, drug entrapment efficiency, drug loading and in-vitro drug release. Percentage cumulative drug release for optimized batch F5 was found to be 85.421 ± 0.054 and followed higuchi model for release of drug.
  • No Thumbnail Available
    Item
    Use of Multimedia in Punjabi Learning System Design
    (Chitkara University Publications, 2018-09-03) Neelam
    In this technology era, students are becoming more efficient in coursework because of a better understanding of the subject materials due to the availability of multimedia packages that make teaching-learning an interesting process. In India, the scope of regional languages is limited only to their regions. Hence, more emphasis has been put on the use of Multimedia to develop the mother tongue. The development of instructional material using Multimedia in the Punjabi Language will help the teachers to procure and use these packages in classroom teaching, to make teaching interesting. Also, this will help the teachers to make a shift from traditional methods of teaching to new computerized methods. Due to this, students will able to retain the concepts for a long time as these methods have proved very effective in other courses too. Furthermore, films and print media also have a great contribution towards the technical teaching of these languages to promote the usage of regional languages at the National and International Level.