Browsing by Author "Anupam Sharma"

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    Antianxiety Activity Evaluation of Hibiscus Sabdariffa Linn. Calyces
    (Chitkara University Publications, 2022-11-10) Gulsheen; Anupam Sharma
    Background: Anxiety is one of the most commonly prevailing psychiatric and behavioural disorders. Evolutionarily, it is regarded as a healthy emotion or behavioural repertoire, which is the outcome of a stressful situation, thereby, helping an individual to cope with a possible risk or a novel situation by increasing awareness and responsiveness. Benzodiazepines, barbiturates, SRIs etc., are used as first line drugs for the management of anxiety, but due to myriad of adverse effects associated with these conventional drugs, inclination of patients towards complementary and alternative medicines (CAMs) has tremendously risen. CAM interventions mainly include herbal remedies.Different parts of Hibiscus sabdariffa have been used traditionally for treating several ailments including mental disorders. Purpose: Keeping in mind the traditional use of H. sabdariffacalyces,the present study was designed to evaluate their antianxiety potential. Methods: Petroleum ether (60-80°C), chloroform, ethanol, and water extracts were prepared using successive Soxhlet extraction and evaluated using elevated plus-maze model. Results: Among all the extracts, ethanol extract showed significant antianxiety activity at a dose of 400 mg/kg. Conclusion: Thus, the study establishes antianxiety activity of H. sabdariffa calyces and also validates their traditional use.
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    Moorva – A Drug Of Controversial Identity: Review
    (Chitkara University Publications, 2022-05-07) Gulsheen; Anupam Sharma
    Introduction: Over the past few years, there has been a huge surge of interest towards Ayurvedic system of medicine, and it has become a subject of intensive research for various aspects. However, variation in the languages and prevalence of folklore medicines has led to confusion in the true identity of different plants having similar name. Moreover, the description of a plant in the ancient literature is found in verses, having ample use of synonyms. These synonyms have caused controversy in the identification of plants and, hence, the correct source of the plant could be misleading. Background: Since herbal products are generally prepared using extracts of plants known for particular activity, the controversial source sometimes may lead to preparation of inefficacious medicines. Review Results: Substantial efforts are being made to standardize the Ayurvedic crude drugs as well as finished Ayurvedic medicines. However, these initiatives imperatively need establishing correct identity of the plant drug. Moorva is an important controversial drug in Ayurveda. Its roots are used for thetreatment of various disorders. Five different plants are considered as Moorva throughout India. Only preliminary pharmacognostic reports are available on these five species. Conclusion: The present review aims at differentiating these five sources of Moorva roots, i.e., C.fragrans, H.isora, M.arenaria, S.roxburghiana and Marsdeniatenacissima.