Browsing by Author "Akhil Sharma"

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    Anti-diabetic Potential of Traditional Herbal Drugs in Polyherbal Formulation–A Review
    (Chitkara University Publications, 2024-04-20) Suryakant Verma; Milind Sharad Pande; Ravinder Kumar Mehra; Deepak Kajla; Akhil Sharma; Ashi Mannan; Manu Grover; Muhammad Tawhid
    Background: Diabetes mellitus, characterized by hyperglycemic symptoms, has emerged as a major global health challenge. The disease’s severity is compounded by both micro- and macrovascular complications associated with hyperglycemia, leading to significant morbidity. Current conventional anti-diabetic medications, while widely prescribed, often demonstrate high failure rates and are associated with adverse pathological effects. Purpose: This paper aims to evaluate the potential of polyherbal formulations in the treatment of diabetes mellitus, addressing the need for alternative therapeutic approaches with enhanced efficacy and reduced side effects. Methods: The study examines various natural extracts and their constituents derived from medicinal plants, focusing on their hypoglycemic properties. Special attention is given to polyherbal formulations, which combine multiple herbs to potentially enhance therapeutic efficacy while reducing individual herb concentrations and associated adverse effects. Results: While numerous herbal medications have been developed for diabetes mellitus treatment, the review identifies a significant gap in scientific validation and medical proof of their efficacy. Polyherbal formulations show promise in enhancing therapeutic action while minimizing adverse events through reduced concentrations of individual herbs. Conclusion: The investigation highlights the potential of polyherbal formulations as an alternative approach to diabetes management. However, there is a crucial need for rigorous scientific validation and clinical trials to establish their efficacy and safety profiles before widespread implementation in diabetes treatment protocols.